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While the medicinal chemists were trying to find new medicines for hypertension treatment, they accidentally found out active molecules that make erections stronger. The unusual effect that was first considered as a side one was turned into the main and this changed the lives of many men.

One of such medicines is Cialis. It was developed after Viagra and has a bit different profile. Here we are going to discuss all the basic information one should know before the administration and utilization of this medicine.

Effects and mechanism of action

An active ingredient of Cialis is tadalafil. Nowadays this medicine is prescribed in the cases of:

• erectile dysfunction;
• benign prostatic hyperplasia;
• pulmonary arterial hypertension.

All these indications for usage are based on the same mechanism. After entering the body, the active ingredient of the drug contributes to the increase of the blood flow, especially in the penis, dilutes the arteries and relaxes the muscles. This action occurs due to the release of nitric oxide, which is stimulated by the medicine.

Actually, this mechanism explains why medicines of this group were created in search of antihypertensive agents. Their main idea and mechanism of action are quite similar. Only Cialis acts quite specifically in the penis area and has a lesser effect on blood pressure in general.

Tadalafil is similar to the earlier analogs like sildenafil and vardenafil in terms of action and pharmacological effect. However, it has a longer half-life (up to 17.5 hours) compared to them. Thus, sildenafil lasts on average 4–5 hours. Therefore, the overall duration of its action is longer. In addition, it is the reason for its prescription for daily therapeutic use in the treatment of pulmonary arterial hypertension.

Administration rules

Cialis is produced as pills for oral intake. There are two main options – 10 and 20 mg.

The average dose for erectile dysfunction is 10 mg approximately half an hour before sexual activity. If this dose does not bring sufficient effect, then a 20 mg pill can be utilized.

The effect of the medicine is revealed after the sexual stimulation. That is why one does not need to predict the exact time of the intercourse to get the desired effect. Moreover, it’s worth mentioning that the effect remains up to 36 hours due to the long half-life of the drug. That is why this medicine is often called a weekend pill and it is important to be careful with the intake and avoid overdose.

Thus, the second dose of Cialis must not be taken earlier than 24 hours after the first one. It is better to wait even longer if there is no need for the effect of the medicine.

Side effects

Possible adverse effects are quite various and can be considered in the following groups:

• hypersensitivity reactions and allergies;
• headaches and dizziness; violation of cerebral circulation, loss of consciousness, ischemic attacks, migraine, seizures, amnesia;
• blurred vision and visual defects, pain in the eyes, their swelling, optic neuropathy;
• ringing in the ears and sudden hearing loss;
• nasal congestion;
• fast heart rate, myocardial infarction, arrhythmia;
• hot flushes and changes in blood pressure;
• dyspepsia and abdominal pain;
• dermatitis;
• back and muscle pain, pain in limbs and chest pain.

Although the list of possible side effects is quite long, their occurrence is not very pronounced and they do not appear often, especially if the medicine is taken from time to time.

However, if any unpleasant sensations are observed, it is necessary to stop the intake and inform the healthcare provider about them. Then, the doctor will advise you on further actions and the possibility of continuing the intake of Cialis.

Contraindications

Due to the mechanism of action and quite a powerful effect on the body, Cialis is prohibited in the following circumstances:

• hypersensitivity to the main ingredient or other components;
• cardiovascular diseases, such as myocardial infarction (within 90 days), angina pectoris, heart failure, uncontrolled arrhythmias, arterial hypotension, after a stroke (within the last 6 months);
• loss of vision as a result of ischemic optic neuropathy.

Patients who use any medicinal forms of organic nitrates and antihypertensive agents should also avoid this medicine as it has the same mechanism of action and effect and may lead to an abrupt decrease in blood pressure.

Those patients, who need to regularly take any other medicines, should also consult their healthcare providers on the possibility of such combinations.

Conclusions

In a nutshell, Cialis is a great option that helps men to feel confident and get back strong erections. This medicine does not act without sexual stimulation. Still, it has a longer duration of effect compared to other similar options. Moreover, it can be utilized on a daily basis if necessary.

Do not forget to consult a healthcare provider on the rules of its intake and get all the positive effects associated with Cialis without any problems.